FIN.data {bionetdata} | R Documentation

## Functional Interaction Network data for human.

### Description

Functional Interaction data obtained from the supplemental materials of a paper written by Wu and colleagues: 'A human functional protein interaction network and its application to cancer data analysis'. Data are represented through a binary named matrix and represent the presence or absence of gene-gene functional interactions. The original network is composed by more than 9000 genes. The network contained in the bionetdata R package is a reduced version containing 2033 nodes and obtained using the walktrap.community function of the R package igraphi. The walktrap.community function is an implementation of a community detection method developed by Pons and Latapy based on a between vertices similarity measure computed by means of a random walk.

### Usage

    data(FIN.data)

### Format

Binary named matrix. Entry `FIN.data[i,j] = 1` if there is a functional interaction between gene i and j, otherwise `FIN.data[i,j] = 0`.

### Source

Wu and colleagues original data are available as : http://genomebiology.com/content/supplementary/gb-2010-11-5-r53-s3.zip

### References

Wu G., Feng X. and Stein L. A human functional protein interaction network and its application to cancer data analysis, Genome Biology 11:R53, 2010.

Pons P. and Latapy M. Computing communities in large networks using random walks, J. of Graph Alg. and App. bf, 10:284-293, 2004.

### Examples

    data(FIN.data);
    FIN.data[1:10,1:10];

[Package bionetdata version 1.0.1 Index]