# Joint Frailty-Copula Models for Tumour Progression and Death in Meta-Analysis

## Documentation for package ‘joint.Cox’ version 3.16

- DESCRIPTION file.

## Help Pages

joint.Cox-package | Joint Frailty-Copula Models for Tumour Progression and Death in Meta-Analysis
cmprskCox.reg | The Competing Risks Version of Penalized Likelihood Estimation under the Joint Cox Models Between Tumour Progression and Death for Meta-Analysis
condCox.reg | Penalized Likelihood Estimation under the Joint Cox Models Between Tumour Progression and Death for Meta-Analysis; A Conditional Copula Approach
dataOvarian | Survival data of 1003 ovarian cancer patients from 4 independent studies.
dataOvarian1 | Data on time-to-recurrence and 158 gene expressions for 912 ovarian cancer patients from 4 independent studies.
dataOvarian2 | Data on time-to-death and 128 gene expressions for 912 ovarian cancer patients from 4 independent studies.
F.KM | Prediction of death using the Kaplan-Meier estimator
F.prediction | Dynamic prediction of death
F.window | Dynamic prediction of death under the joint frailty-copula model
F.window.Weibull | Dynamic prediction of death under the joint frailty-copula model (the Weibull baseline hazard functions)
F.windows | Dynamic prediction of death under the joint frailty-copula model
F.windows.Weibull | Dynamic prediction of death under the joint frailty-copula model (the Weibull baseline hazard functions)
I.spline | I-spline basis function
joint.Cox | Joint Frailty-Copula Models for Tumour Progression and Death in Meta-Analysis
jointCox.indep.reg | Penalized Likelihood Estimation under the Joint Cox Models Between Tumour Progression and Death for Meta-Analysis
jointCox.reg | Penalized Likelihood Estimation under the Joint Cox Models Between Tumour Progression and Death for Meta-Analysis
jointCox.Weibull.reg | Weibull-based Likelihood Estimation under the Joint Cox Models Between Tumour Progression and Death for Meta-Analysis
M.spline | M-spline basis function
splineCox.reg | Fitting the Cox model for survival data using a penalized spline model
Weibull.simu | Simulating data from the Weibull joint frailty-copula model