Group Sequential Design Class for Clinical Trials

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Documentation for package ‘seqmon’ version 2.3

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seqmon-package seqmon
alphaspend Function that calculates the upper boundaries for efficacy
alphaspendf The default alpha spending function
betaspend Function that calculates the lower boundaries for futility
betaspendf The default beta spending function
calcBoundaries Function for calculating the efficacy and futility boundaries
calcBoundaries-method Class '"sequential.design"'
curtail Generic function that calculates the probability to declare efficacy at the end of study given the Z value at the current look
curtailDesign Function for calculating the probability for efficacy given known information
curtailDesign-method Class '"sequential.design"'
getProbabilities Function that calculates the cumulative probabilities to declare efficacy and futility
getProbabilities-method Class '"sequential.design"'
plotBoundaries Function that plots the efficacy and futility boundaries
plotBoundaries-method Class '"sequential.design"'
print Function that displays the features of the design
print-method Class '"sequential.design"'
seqmon Generic function that calculates the cumulative alpha and beta spending
sequential.design The sequential design class
sequential.design,sequential.design-class Class '"sequential.design"'
sequential.design-class Class '"sequential.design"'
setAlphaspendfString Function that Sets the expression of the base alpha spending function as a string
setAlphaspendfString-method Class '"sequential.design"'
setBaseAlphaspendf Function that sets the base alpha spending function
setBaseAlphaspendf-method Class '"sequential.design"'
setBaseBetaspendf Function that sets the base beta spending function
setBaseBetaspendf-method Class '"sequential.design"'
setBetaspendfString Function that sets the expression of the base beta spending function as a string
setBetaspendfString-method Class '"sequential.design"'
setCurrentLook Function that sets the current look number
setCurrentLook-method Class '"sequential.design"'
setDatestamp Function that sets the date stamp of the design object
setDatestamp-method Class '"sequential.design"'
setNoncentrality Function that sets the noncentrality parameter
setNoncentrality-method Class '"sequential.design"'
setTimes Function that sets the look times
setTimes-method Class '"sequential.design"'
summary Function that shows the cumulative probabilities for efficacy and futility
summary-method Class '"sequential.design"'
updateDesign Function that updates the design
updateDesign-method Class '"sequential.design"'