alpha {coin} | R Documentation |
Levels of expressed alpha synuclein mRNA in three groups of allele lengths of NACP-REP1.
alpha
A data frame with 97 observations on 2 variables.
alength
allele length, a factor with levels "short"
, "intermediate"
and "long"
.
elevel
expression levels of alpha synuclein mRNA.
Various studies have linked alcohol dependence phenotypes to chromosome 4. One candidate gene is NACP (non-amyloid component of plaques), coding for alpha synuclein. Bönsch et al. (2005) found longer alleles of NACP-REP1 in alcohol-dependent patients compared with healthy controls and reported that the allele lengths show some association with levels of expressed alpha synuclein mRNA.
Bönsch, D., Lederer, T., Reulbach, U., Hothorn, T., Kornhuber, J. and Bleich, S. (2005). Joint analysis of the NACP-REP1 marker within the alpha synuclein gene concludes association with alcohol dependence. Human Molecular Genetics 14(7), 967–971. doi: 10.1093/hmg/ddi090
Hothorn, T., Hornik, K., van de Wiel, M. A. and Zeileis, A. (2006). A Lego system for conditional inference. The American Statistician 60(3), 257–263. doi: 10.1198/000313006X118430
## Boxplots boxplot(elevel ~ alength, data = alpha) ## Asymptotic Kruskal-Wallis test kruskal_test(elevel ~ alength, data = alpha)