alzheimer {coin} | R Documentation

## Smoking and Alzheimer's Disease

### Description

A case-control study of smoking and Alzheimer's disease.

### Usage

    alzheimer

### Format

A data frame with 538 observations on 3 variables.

`smoking`

  a factor with levels `"None"`, `"<10"`, `"10-20"` and `">20"` (cigarettes per day).

`disease`

  a factor with levels `"Alzheimer"`, `"Other dementias"` and `"Other diagnoses"`.

`gender`

  a factor with levels `"Female"` and `"Male"`.

### Details

Subjects with Alzheimer's disease are compared to two different control groups with respect to smoking history. The data are given in Salib and Hillier (1997, Tab. 4).

### Source

Salib, E. and Hillier, V. (1997). A case-control study of smoking and Alzheimer's disease. International Journal of Geriatric Psychiatry 12(3), 295–300. doi: 10.1002/(SICI)1099-1166(199703)12:3<295::AID-GPS476>3.0.CO;2-3

### References

Hothorn, T., Hornik, K., van de Wiel, M. A. and Zeileis, A. (2006). A Lego system for conditional inference. The American Statistician 60(3), 257–263. doi: 10.1198/000313006X118430

### Examples

    ## Spineplots
    op <- par(no.readonly = TRUE) # save current settings
    layout(matrix(1:2, ncol = 2))
    spineplot(disease ~ smoking, data = alzheimer,
              subset = gender == "Male", main = "Male")
    spineplot(disease ~ smoking, data = alzheimer,
              subset = gender == "Female", main = "Female")
    par(op) # reset

    ## Asymptotic Cochran-Mantel-Haenszel test
    cmh_test(disease ~ smoking | gender, data = alzheimer)

[Package coin version 1.3-0 Index]