ocarcinoma {coin} | R Documentation

## Ovarian Carcinoma

### Description

Survival times of 35 women suffering from ovarian carcinoma at stadium II and IIA.

### Usage

    ocarcinoma

### Format

A data frame with 35 observations on 3 variables.

`time`

  time (days).

`stadium`

  a factor with levels `"II"` and `"IIA"`.

`event`

  status indicator for `time`: `FALSE` for right-censored observations and `TRUE` otherwise.

### Details

Data from Fleming et al. (1980) and Fleming, Green and Harrington (1984). Reanalysed in Schumacher and Schulgen (2002).

### Source

Fleming, T. R., Green, S. J. and Harrington, D. P. (1984). Considerations for monitoring and evaluating treatment effects in clinical trials. Controlled Clinical Trials 5(1), 55–66. doi: 10.1016/0197-2456(84)90150-8

Fleming, T. R., O'Fallon, J. R., O'Brien, P. C. and Harrington, D. P. (1980). Modified Kolmogorov-Smirnov test procedures with application to arbitrarily right-censored data. Biometrics 36(4), 607–625. doi: 10.2307/2556114

### References

Schumacher, M. and Schulgen, G. (2002). Methodik Klinischer Studien: Methodische Grundlagen der Planung, Durchführung und Auswertung. Heidelberg: Springer.

### Examples

    ## Exact logrank test
    lt <- logrank_test(Surv(time, event) ~ stadium, data = ocarcinoma,
                       distribution = "exact")

    ## Test statistic
    statistic(lt)

    ## P-value
    pvalue(lt)

[Package coin version 1.3-0 Index]