NMFfitXn-class {NMF} | R Documentation

## Structure for Storing All Fits from Multiple NMF Runs

### Description

This class is used to return the result from a multiple run of a single NMF algorithm performed with function `nmf` with option `keep.all=TRUE` (cf. `nmf`).

### Details

It extends both classes `NMFfitX` and `list`, and stores the result of each run (i.e. a `NMFfit` object) in its `list` structure.

IMPORTANT NOTE: This class is designed to be read-only, even though all the `list`-methods can be used on its instances. Adding or removing elements would most probably lead to incorrect results in subsequent calls. Capability for concatenating and merging NMF results is for the moment only used internally, and should be included and supported in the next release of the package.

### Slots

.Data

  standard slot that contains the S3 `list` object data. See R documentation on S3/S4 classes for more details (e.g., `setOldClass`).

### Methods

algorithm

  `signature(object = "NMFfitXn")`: Returns the name of the common NMF algorithm used to compute all fits stored in `object`

  Since all fits are computed with the same algorithm, this method returns the name of algorithm that computed the first fit. It returns `NULL` if the object is empty.

basis

  `signature(object = "NMFfitXn")`: Returns the basis matrix of the best fit amongst all the fits stored in `object`. It is a shortcut for `basis(fit(object))`.

coef

  `signature(object = "NMFfitXn")`: Returns the coefficient matrix of the best fit amongst all the fits stored in `object`. It is a shortcut for `coef(fit(object))`.

compare

  `signature(object = "NMFfitXn")`: Compares the fits obtained by separate runs of NMF, in a single call to `nmf`.

consensus

  `signature(object = "NMFfitXn")`: This method returns `NULL` on an empty object. The result is a matrix with several attributes attached, that are used by plotting functions such as `consensusmap` to annotate the plots.

dim

  `signature(x = "NMFfitXn")`: Returns the dimension common to all fits.

  Since all fits have the same dimensions, it returns the dimension of the first fit. This method returns `NULL` if the object is empty.

entropy

  `signature(x = "NMFfitXn", y = "ANY")`: Computes the best or mean entropy across all NMF fits stored in `x`.

fit

  `signature(object = "NMFfitXn")`: Returns the best NMF fit object amongst all the fits stored in `object`, i.e. the fit that achieves the lowest estimation residuals.

.getRNG

  `signature(object = "NMFfitXn")`: Returns the RNG settings used for the best fit.

  This method throws an error if the object is empty.

getRNG1

  `signature(object = "NMFfitXn")`: Returns the RNG settings used for the first run.

  This method throws an error if the object is empty.

minfit

  `signature(object = "NMFfitXn")`: Returns the best NMF model in the list, i.e. the run that achieved the lower estimation residuals.

  The model is selected based on its `deviance` value.

modelname

  `signature(object = "NMFfitXn")`: Returns the common type NMF model of all fits stored in `object`

  Since all fits are from the same NMF model, this method returns the model type of the first fit. It returns `NULL` if the object is empty.

nbasis

  `signature(x = "NMFfitXn")`: Returns the number of basis components common to all fits.

  Since all fits have been computed using the same rank, it returns the factorization rank of the first fit. This method returns `NULL` if the object is empty.

nrun

  `signature(object = "NMFfitXn")`: Returns the number of runs performed to compute the fits stored in the list (i.e. the length of the list itself).

purity

  `signature(x = "NMFfitXn", y = "ANY")`: Computes the best or mean purity across all NMF fits stored in `x`.

runtime.all

  `signature(object = "NMFfitXn")`: If no time data is available from in slot ‘runtime.all’ and argument `null=TRUE`, then the sequential time as computed by `seqtime` is returned, and a warning is thrown unless `warning=FALSE`.

seeding

  `signature(object = "NMFfitXn")`: Returns the name of the common seeding method used the computation of all fits stored in `object`

  Since all fits are seeded using the same method, this method returns the name of the seeding method used for the first fit. It returns `NULL` if the object is empty.

seqtime

  `signature(object = "NMFfitXn")`: Returns the CPU time that would be required to sequentially compute all NMF fits stored in `object`.

  This method calls the function `runtime` on each fit and sum up the results. It returns `NULL` on an empty object.

show

  `signature(object = "NMFfitXn")`: Show method for objects of class `NMFfitXn`

### See Also

Other multipleNMF: `NMFfitX1-class`, `NMFfitX-class`

### Examples

    # generate a synthetic dataset with known classes
    n <- 20; counts <- c(5, 2, 3);
    V <- syntheticNMF(n, counts)

    # get the class factor
    groups <- V$pData$Group

    # perform multiple runs of one algorithm, keeping all the fits
    res <- nmf(V, 3, nrun=3, .options='k') # .options=list(keep.all=TRUE) also works
    res

    summary(res)
    # get more info
    summary(res, target=V, class=groups)

    # compute/show computational times
    runtime.all(res)
    seqtime(res)

    # plot the consensus matrix, computed on the fly
    ## Not run:  consensusmap(res, annCol=groups)

[Package NMF version 0.20.6 Index]